Raising NAD+: What It Does, What It Doesn't Prove Yet

NMN and NR are precursor molecules — raw materials — that the body converts into NAD+, a molecule every cell needs to turn food into usable energy and to repair damaged DNA, and which reliably declines with age. Both NMN and NR reliably raise blood NAD+ levels in trials; that part is well-established. What's not yet established is whether raising NAD+ this way produces a meaningful lifespan or healthspan benefit in otherwise healthy people — the Longevity guide's Section 6 covers that open question in full.